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doi: 10.1038/nri.2016.70 61 AdamikJMunsonPVHartmannFJCombesAJPierrePKrummelMFet al

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The rearrangement is accompanied by a cis-trans isomerization of this proline, which likely increases the energy required for the transition between the 2 states, and may play a role in the stabilization of the active conformation at the water/lipid interface

Cheung CP, Nardone M, Lee JB, Baker RE, Millar PJ, Burr JF

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