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As a neurosurgeon, I have frequently observed the consequences of oxidative stress in traumatic brain injuries, ruptured intracranial aneurysms (widening of blood vessels), and other major insults to the brain, Joseph Maroon, clinical professor of neurological surgery at the University of Pittsburgh Medical Center, Pennsylvania, US, told PTI in an email

In addition, gene expression profiles of samples from the same cell type showed a high degree of correlation

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wustl.edu Cellular mechanisms to clear misfolded proteins, and therapies to minimize toxicity by stimulating degradation of misfolded proteins As a physician-scientist, David Perlmutter is internationally recognized for his research on alpha-1 antitrypsin deficiency (ATD), a genetic disorder in which accumulations of a misfolded protein can cause severe liver damage