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The gut microbiome in myalgic encephalomyelitis (ME)/chronic fatigue syndrome (CFS)

Avoid direct sunlight and hot environments, as excessive heat can affect its longevity

Other exploratory treatment options that may have benefit but are not sufficiently supported by clinical trial data include physical activity, acupuncture, scrambler therapy, pregabalin/gabapentin, topical gel treatments, tryicyclic antidepressants, and oral cannabinoids

Pyruvate then either becomes lactate or enters the mitochondria for further oxidation in the citric acid (TCA) cycle

Future research should explore interactions between pollutants (i.e., synergistic, additive, antagonistic), wider range of pollutant concentrations, exposure times, and additional endpoints