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Furthermore, expression of tissue inhibitors of metalloproteinases (TIMPs) is increased by myofibroblasts, leading to reduced extracellular matrix degradation [257, 258]

The net result of these processes is an increase in serum concentrations, which, by the way, has been demonstrated to escalate the risk and/or severity of ADRs associated to exposure to such drugs (DrugBank Clinical API Plugins, 2024)

Work on the chicken RSV was extended to similar viruses in mammals, so that many researchers at that time believed that RT activity was a new, highly sensitive tool for detecting similar viruses in human leukaemia and cancer