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After exposure to the supernatant obtained from BV-2 cells treated with LPS, SH-SY5Y cells exhibited a notable decrease in their viability and an elevation in apoptosis rate

Patients were initially administered with the starting dose of 500 mg/day of curcumin and if no apparent toxicity occurred, increments in dosage were done step-wise in the order of 1000, 2000, 4000, 8000 to 12000 mg/day

doi:10.1016/j.envpol.2017.04.015 Lin J, Li HX, Xia J, Li XN, Jiang XQ, Zhu SY, Ge J, Li JL (2016b) The chemopreventive potential of lycopene against atrazine-induced cardiotoxicity: modulation of ionic homeostasis

Reactive oxygen species and the free radical theory of aging

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