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Its known to trigger a cascade of responses within the skin, encouraging the synthesis of key proteins in the extracellular matrix, including collagen, elastin, and glycosaminoglycans

The contradictory response of glutathione gel in the treatment of melasma in different studies may be attributed to the difference in stability, absorption, penetration of glutathione and affected by the different vehicle (soap, cream, gel or lotion) rather than the efficacy of glutathione itself

, Delgadillo A., GiovagnoliVicua C., QuispeFuentes I., and ZuraBravo L

10.1016/0014-5793(93)80958-w [DOI] [PubMed] [Google Scholar] Korhonen L., Sjholm U., Takei N., Kern M

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