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145 Telaglenastat, a glutaminase inhibitor, was also evaluated in combination with everolimus (TelaE) in a phase I trial of advanced/metastatic renal cell carcinoma (mRCC), and TelaE therapy was well tolerated in patients previously treated with TKIs and checkpoint inhibitors (NCT03163667)

Harris CB, Chowanadisai W, Mishchuk DO, Satre MA, Slupsky CM, Rucker RB

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However, hydroxyl radical may still be formed, i.e., during the reaction of Fe 2+ DTPA with hydrogen peroxide (Cohen and Sinet, 1982