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Discovery and pharmacological characterization of a new class of prolyl-tRNA synthetase inhibitor for anti-fibrosis therapy

The doseresponse relationship was non-linear, with risk rising rapidly at lower intake levels and attenuating at higher exposures (Fig

doi:10.1097/mcg.0b013e3181e883dd 66Sternthal MB, Murphy SJ, George J, et al

In our study, transient ROS-scavenging was not able to revert these modifications and to reinstate the functionality of these cells

In this work we assume that the ensemble of multi-task convolutional neural networks makes reliable predictions up to three mutation steps from the closest training-set analogue sequence