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Sci Rep 6(1):35539

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Inhibition of DHHC20-Mediated EGFR Palmitoylation Creates a Dependence on EGFR Signaling

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TS: Conceptualization, Funding acquisition, Supervision, Writing review & editing

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Documented clinical safety signals across the peptide class include a halted clinical trial following a fatal cardiac event, case reports of melanoma and kidney dysfunction, and a documented death following intravenous administration

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