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All of the authors approved the final manuscript

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Erastin, one of the earliest discovered ferroptosis inducers, inhibits system Xc - (SLC7A11/SLC3A2), thereby impairing GSH synthesis, leading to ROS accumulation and inducing GBM cell death ( 2+ levels, increased GSH levels, and suppressed expressions of ferroptosis-related proteins such as GPX4, NRF2, and SLC7A11 ( RAS-selective lethal 3 (RSL3) is a known ferroptosis inducer

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The anticancer agent 3-bromopyruvate: a simple but powerful molecule taken from the lab to the bedside

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Liposomal-based: As discussed, this is the gold standard for glutathione absorption

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The results of this study may contribute to our understanding of the complex interaction between exercise, nutrition and mitochondrial health and pave the way for future research in this area

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