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Intralesional therapies Collagenase clostridium histolyticum (CCH) CCH is a purified bacterial enzyme which selectively breaks down collagen and therefore can break down or soften the plaque in PD [29]

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Despite the lack of further confirmation, 17-estradiol, adenosine receptor A2B agonist, and ROCK inhibitor have shown to be effective for acute PD

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