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Studies have shown that NOS knockout aggravates bleomycin (BLM)-induced fibrosis, whereas NO supplementation mitigates tissue damage [82]

The therapy for this ultra-rare disease uses a similar strategy to Intellias liver-targeting treatments for hATTR and HAE: it consists of a Cas12i2 nuclease and guide RNA encapsulated in a lipid nanoparticle (LNP)

As an emerging type of luminescent materials, CLgens show uncommon properties, such as non-conjugated structures, clustered emitting species, unmatched absorption and excitation spectra, excitation-dependent emission, and RTP phenomenon

Based on these data, a mean milk-to-plasma ratio of 0.21 was derived (Degen et al