oxidized glutathione melanin Modulating skin colour: role of the thioredoxin and systems in regulating melanogenesis oxidized glutathione (GSH/GSSG) ratio serves as an indicator of oxidative stress Glutathione as a depigmenting agent:

Hayes JD, McLellan LI: Glutathione and glutathione-dependent enzymes represent a coordinately regulated defense against oxidative stress

Analogously, in Streptococcus suis serotype 2 models, TrxC modulates AGE-induced neurotoxicity via phosphatidylinositol-4,5-bisphosphate 3-kinase (PI3K)/protein kinase B (Akt)/mTOR pathway regulation, thereby controlling macrophage autophagic responses (134)

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A trend toward even lower mortality was found in people who consumed higher amounts of mushrooms