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Clancy, J.P

Cell lysates were obtained using TRIzolTM reagent (15596026, Invitrogen, CA, America) and preserved at 80 C for subsequent analysis

The actions of adiponectin in suppressing gluconeogenesis and enhancing lipid oxidation are related to the activation of adenosine monophosphate-activated protein kinase (AMPK) and the inhibition of acetyl-CoA carboxylase (ACC) in liver and muscle (Yamauchi et al., 2002)