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Notably, COMT enzymes are most active in the liver and kidneys, but are also present in the pylorus of the stomach and in the small intestine, where they participate in the methylation of available phenolic substrates ( Glucuronidation is the predominant phase II metabolic pathway for tea (poly) phenols

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The AOC emphasizes cultural humility, community resource integration, and evidence-based approaches to addressing health disparities

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