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PLoS One 3 , e2935 (2008)

Endosomes regulate immune homeostasis through receptor traffic and signal transduction, antigen processing, cytokine secretion, and cellular metabolism

For some patients, understanding this single gene is a light-bulb moment that explains why standard B-vitamin formulas never seemed to help or even made them feel worse

Likewise, the randomized trials largely evaluated fixed antibiotic regimens rather than individualized combination antimicrobial therapy based on the patients clinical presentation