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Parkinsons Disease (PD) PD is a movement disorder marked by loss of dopaminergic neurons in the midbrain and accumulation of -synuclein aggregates (Lewy bodies) [145, 146]

Aberrant methylation patterns have been linked to improper gene activation or silencing, which may contribute to the development of HT and PPT [76, 77]

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Furthermore, the exogenous addition of GABA also favored JEV propagation in Neuro2a cells, owing to the immunosuppressive effect of GABA on neurons

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