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Its often paired with vitamin C and other antioxidants, but before combining with other supplements or medications, its best to consult a healthcare provider to avoid potential interactions

10.1016/j.psj.2020.09.074 3

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Another study showed that by using an agent to inhibit phosphodiesterase-5, that the augmentation of NO-cGMP signaling increased protein synthesis and reduced fatigue in human skeletal muscle [20]