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Glutathione and Alpha-Lipoic Acid In addition to scavenging free radicals, glutathione is also involved in recycling vitamins C and E.* Alpha-lipoic acid plays an essential role in mitochondrial dehydrogenase reactions, reacts with reactive oxygen species, and interacts with vitamin C and glutathione to recycle vitamin E.* The following table highlights two studies that looked at the effects of co-supplementation with glutathione and alpha-lipoic acid

There was no difference in litter size between 2-month-old S8/Control and S8/ Gss / male mice

Kummer E, Ban N

These effects of irisin in inflammatory conditions suggest potential therapeutic applications for irisin in the context of depression-related neuroinflammation