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L-Arginine and Alzheimers Disease. International Journal of Clinical and Experimental Pathology 2.3 (2009): 211238

Damage to the nerves If a lack of B12 in the body causes damage to the myelin sheath surrounding our nerves, the feet may experience numbness, pins and needles, reduced sensation and muscle weakness

This is a problem because high levels of this in the blood can cause damage to the heart, joints, and liver

Rajpurkar P, Yang J, Dass N, Vale V, Keller AS, Irvin J, Taylor Z, Basu S, Ng A, Williams LM (2020) Evaluation of a machine learning model based on pretreatment symptoms and electroencephalographic features to predict outcomes of antidepressant treatment in adults with depression: a prespecified secondary analysis of a randomized clinical trial