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Description

PF00299804, an irreversible pan-ERBB inhibitor, is effective in lung cancer models with EGFR and ERBB2 mutations that are resistant to gefitinib

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albicans translocates to the host cytoplasm and binds to TBK1, disrupting TBK1-mediated phosphorylation of IRF3

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10.1038/nrneurol.2013.246 Nat

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