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Although the primary function of DNMT1 is maintenance methylation, it also participates in de novo methylation in specific contexts, such as during oocyte development (Li et al., 2018) and the regulation of retrotransposons (Haggerty et al., 2021)

The toxicity of Se is critically dependent on its redox state and concentration, making it difficult to use pharmacologically

Marked elevations in liver function test results (e.g., AST [SGOT] and ALT [SGPT]), occurred on 2 occasions following administration of high doses (total doses: 106 and 250 g over 3-4 days) of acetylcysteine rectally and via nasogastric tube in a 3-year-old boy with cystic fibrosis

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Clough, S