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Cytoprotective activity against MPP + -induced cytotoxicity SH-SY5Y cells grown in 96-well plates at a density of 4 10 4 cells/well for 24 h were pretreated with blank LPs, free ASX, ASX-LPs, or Lf-ASX-LPs (equivalent to 18 M ASX) for 6 h, incubated with 2 mM MPP + for 24 h, and cell viability was measured using the MTT assay

[4] The peptide survives digestion long enough to act on the mucosa, but clears too rapidly to accumulate in systemic circulation

Consistent timing helps establish steady-state levels

Single, dual and triple agonists side by side