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To evaluate the similarity of the samples in each infection stage, hierarchical clustering analysis that visualized the Euclidean distance between all the samples was calculated from the regularized-logarithm transformation (rlog) using the pheatmap package in R

In the case of doxorubicin resistant cancer, SAMe treatment can sensitize tumoral cell lines to radiation-induced apoptosis by modifying global DNA hypomethylation profile [146]

Comparison of quantitative variables between the two groups was performed by independent t -test, paired t -test, and qualitative variables by Chi-square test

Users who achieved results at 2% might maintain at 1%, preserving benefits while reducing product cost and minimizing long-term skin exposure

Administer GONAL-f subcutaneously in the abdomen, upper arm, or upper leg as described in Patient Information and Instructions for Use