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W modelach zwierzcych opisano wpyw na zachowania zwizane z lkiem i depresj, a take interakcje z lekami psychotropowymi

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However, interestingly, in the cargo-binding region next to F396, the pocket is divided by residue pairs Y232, V400, and E403 aligning directly each side of the pocket with the two pathways separated by the TM6 linking pairs that are present in our other CtAtm1 structures (Fig