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10.1155/2012/936486 3 AliK.MalteseF.ChoiY

Durvalumab with or without tremelimumab in combination with chemotherapy as first-line therapy for metastatic non-small cell lung cancer: the phase III POSEIDON study

Research suggests that oral glutathione supplementation may help increase insulin sensitivity in individuals with and without type-2 diabetes

Another associated problem is the need for an additional purification step to isolate the POI from the cleaved affinity tag and the protease used, although this has also been largely solved via the strategic addition of His tags on commercially available protease enzymes