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FIGURE 6 FIGURE 7 Glutathione Peroxidase 1 Inhibits the NF-B Pathway to Protect Against Peroxynitrite-Induced Spiral Ganglion Neurons Damage The transcription factor NF-B plays a vital role in cellular death and survival under oxidative stress conditions (Li and Karin, 1999), and the activation of NF-B can promote cell death (Schneider et al., 1999

10.3892/ijmm.2022.5132 [DOI] [PMC free article] [PubMed] [Google Scholar] 206.Yilmaz N, Coban DT, Bayindir A, Erol MK, Ellidag HY, Giray O, et al

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However, the enigma created by the presence of different isoforms of APX needs to be resolved and further studies are required to delineate the genetic regulation of APX gene expression, in response to different types of stresses