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Evidence indicates that indoleamine 2,3-dioxygenase (IDO), an enzyme responsible for the breakdown of tryptophan, serves as an immune checkpoint molecule

Inflamm Bowel Dis 2013;19:614620.PubMed 28

In a small Phase III trial in neurotrophic keratopathy (a condition where the cornea loses sensation and fails to heal), complete healing at four weeks occurred in 6 of 10 patients on thymosin 4 eye drops versus 1 of 8 on placebo [3]