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This review systematically elucidates the prevailing diagnostic criteria, summarizes recent advances in understanding the potential pathophysiological mechanisms, and evaluates pharmacological and non-pharmacological interventions, and symptom-based assessment and management strategies

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The CNRQ of SLC25A20 remained at the baseline level throughout the trial in CAR, whereas the value increased significantly after LPS injection and returned to the initial level 14 d after immune challenge in CON

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