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Hence, given that the reported bioavailability of the drug is around 50%-60%, there is still a level of faecal recovery of 20%-30%, suggesting a significant proportion remains available to interact with GI microbiota

A deficiency of TNSALP in HPP leads to decreased overall ALP activity and subnormal ALP levels

A healthy lifestyle is the basis to optimise health outcomes regardless of WL increased levels of physical activity have multiple health benefits including improvement of body composition, physical function and cardiorespiratory fitness, and a balanced Mediterranean diet may be associated with cardiovascular benefits [105]

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All quantitative safety findings derive from animal and in-vitro models