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Disclosures: Sudeep Tanwar: Nothing to Disclose, Walter Gregory: Nothing to Disclose, The ELUCIDATE Investigators: Nothing to Disclose, Peter Selby: Nothing to Disclose, William Rosenberg: Nothing to Disclose 2039 SERUM THROMBOSPONDIN 2 AND INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 7 PREDICT ADVANCED LIVER FIBROSIS IN PATIENTS WITH COMMON VARIABLE IMMUNODEFICIENCY Rambabu Surabattula 1 Valentina Strohmeier 2 Anna-Maria Globig 2 Sudha Myneni 1 Maximilian Heeg 2 Gerhard Kindle 2 Sigune Goldacker 2 Caroline von Spee-Mayer 2 Michele Proietti 3 Birke Bausch 2 Dominik Bettinger 2 Michael Schulthei 2 Robert Thimme 2 Klaus Warnatz 2 Detlef Schuppan 1 , 1 University Medical Center Mainz, 2 University Medical Center Freiburg, 3 Hannover Medical School Background: Timely detection of segmental fibrosis and portal hypertension as a manifestation in a significant subgroup of patients with CVID (Common Variable Immunodeficiency) is a challenge, as it is usually not associated with classic liver cirrhosis

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The concentration of Mouse MPIF2 in the samples is then determined by comparing the OD of the samples to the standard curve

This connection has been previously described alongside functional deficits in the 6-OHDA model of PD (Tuppy et al., 2015

[23] Cyanocobalamin is usually converted to hydroxocobalamin in the serum, whereas hydroxocobalamin is converted to either methylcobalamin or adenosylcobalamin