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An alternative strategy would be to explore indirect methods such as the inhibition of upstream miRNAs and/or protein kinases, along with directly targeting Nrf2

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Khan F, Pandey P, Verma M, Ramniwas S, Lee D, Moon S, et al

In addition, MT inhibited RIR-induced ferroptosis by decreasing ROS and Fe 2+ levels and increasing GSH levels through the regulation of the p53/Slc7a11/Alox12 signaling pathway (375)