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In developed countries, excessive calorie intake and frequent consumption of unhealthy foods, associated with a sedentary lifestyle, have caused an increase in the prevalence of obesity, which in turn predisposes to several non-communicable diseases, such as cardiovascular disease, diabetes, hypertension, and chronic kidney disease [9]

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On histology, PSC is characterised by periductal fibrosis, bile duct proliferation, periportal inflammatory, dutopaenia and varying degrees of fibrosis

Stop using facial scrubs and exfoliants the week before the peel