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The funding source had no role in the design, conduct of the study, collection, management, analysis and interpretation or preparation, review, or approval of the manuscript

Recent advancements in single-cell multiomics techniques 207 , which can simultaneously profile the (epi)genome, transcriptome and other molecular layers, have been instrumental in inferring the intricate interplay among chromatin, transcription factors and genes generating a complex regulatory circuit represented as GRNs

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