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Catalpol administration to mice also inhibited HPA axis hyperactivity (reflected in lower levels of corticosterone, ACTH, and CRH), central inflammation, and oxidative damage via regulation of the NF-B and Nrf2 pathways, producing antidepressant effects in mice injected with corticosterone [60]

Schliep KC, Mumford SL, Peterson CM, Chen Z, Johnstone EB, Sharp HT, et al

Dalto, Francisco Wanderley G

Scrophulariae Radix is traditionally believed to possess detoxifying and lump-resolving properties, suggesting potential therapeutic benefits for treating thyroid diseases

Emerging paramyxoviruses: receptor tropism and zoonotic potential