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Mouse Biol

Huang F, Zhang Q, Ma H, Lv Q, Zhang T

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Subsequently, it causes cellular damage in the form of lipid peroxidation, proteolysis, and membrane devastation [52]

Furthermore, quantification of hepatocellular vacuolation (a characteristic of cellular degeneration observed through tissue pathology staining) at the 2-h time point revealed a 1.5-fold greater area of liver degeneration in hepsin / mice compared with wild-type mice, which increased to ~ 2.5-fold greater by the 6-h time point (Fig