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Many patients find the experience more relaxing with a loved one beside them

It is designed to act locally and systemically at extremely low concentrations, using the smallest possible molecular mass to drive a maximal cellular response [5]

This happens more often than anyone wants to admit

J Biol Chem 2008;283:1193511946

They confirmed the long-lasting antidepressant effect of a single injection of ketamine and observed changes in synaptic plasticity resulting from persistent changes in dendritic spines and synapse-associated proteins