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Management options: dose reduction, switch to a lower-peak formulation (such as gel), or therapeutic phlebotomy

Evidence grade Preclinical evidence only Regulatory status No FDA-approved indication and no exact-name ClinicalTrials.gov record located as of July 12, 2026

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La B12 peut apparatre comme normale, mais si le mcanisme de transport nest pas satur, alors en cas de dficit alimentaire, la transcobalamine pourrait ne pas dlivrer la vitamine aux tissus (carence tissulaire), tandis que les valeurs sanguines continueraient dapparatre normales