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Summary and future directions The ability of GHK and its Cu chelate to promote skin remodeling, wound healing and regeneration, and its prominent antioxidant and anti-inflammatory effects are qualities that will help enhance healthy aging [28-31]

Morphologically, activated microglia exhibited hallmark features of a pro-inflammatory state, including enlarged somata, retracted processes, and increased cell density

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c-MET receptor was substantially downregulated by siRNA-MET which also correlated with a concomitant inhibition of p-MET as well as its downstream signalling molecules p-AKT, p-ERK1/2, and p-S6 kinase (Figure 6A)