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After infection, all mice were single-caged to prevent transfer of disease between mice and allow for appropriate diarrhea scoring

Its primary effects are mediated through three transcription factors from the GLI family, which includes GLI1, GLI2, and GLI3 (Omenetti et al., 2011

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BH4 not only takes part in numerous central metabolic processes by serving as an important cofactor for various enzymes (96), but also downregulates the oxidative degradation of phospholipids contained two PUFA tails by serving as a direct antioxidant and an important regulator in CoQ 10 synthesis (94), thus inhibiting lipid peroxidation and inducing ferroptosis