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doi: 10.3389/fphar.2025.1590797 Received 10 March 2025 Accepted 10 July 2025 Published 31 July 2025 Volume 16 - 2025 Edited by Joan Villena Garca, Universidad de Valparaso, Chile Reviewed by Adnan Amin, Yeungnam University, Republic of Korea Guoxin Qu, First Affiliated Hospital of Hainan Medical University, China Updates Copyright 2025 Bu, Li, Wang, Yu, Liu, Sun, Sun, Gong, Luo and Yue

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Notably, SIRT1, which serves as a pivotal modulator in the promotion of healthspan, captures scientific intrigue largely because of its ability to orchestrate a multitude of signaling cascades

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