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* Correspondence: Sharon Baumel-Alterzon, [email protected] These authors have contributed equally to this work Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

These approaches improve bioavailability, stability, and retinal targeting, overcoming major limitations in conventional administration

Figure 5 Monocyte secretion of IL-1 and IL-18 as a result of NLRP3 inflammasome activation requires mitochondrial-derived ROS and is commonly associated with an imbalance of cellular redox status ( high CD16 monocytes by imaging flow cytometry

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The three families from France were recruited as part of a larger cohort study for which ethical approval was obtained from the Comit de Protection des Personnes