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Arginine deficiency leads to limited activation of immune cells such as T cells (146) and NK cells (147), thereby impairing the immune response and promoting tumour development and metastasis

A weakly informative prior for between-trial heterogeneity ( ), specifically an HN prior with a scale of 0.5, was applied 29 , whereas uninformative priors were used for treatment and interaction effects

this is termed a secondary IV, or IV piggyback

Many trials recruited younger participants outside our target demographic of 3065 years, limiting the available evidence for middle-aged and older adults

In addition, total flavonoids from Acacia and Propolis also exert protective effects on liver injury [55]