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Restless legs syndrome (RLS), also known as Willis-Ekbom disease, is a common movement disorder that affects 2-4% of children and 5-10% of adults in the U.S

[DOI] [PMC free article] [PubMed] [Google Scholar] 103.Poor CL, Bierer TL, Merchen NR, Fahey GC, Murphy MR, Erdman JW

The accumulation of iron is a major cause of excess free radical generation in the RPE and is strongly linked to the development of AMD (225)

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Two randomized controlled trials published in JAMA Network Open by Imperial College London (2022 and 2023) found that kisspeptin significantly changed brain activity in key sexual processing regions in both women and men with low libido, with no reported adverse effects in either study