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Such cases may represent patients who have not previously been able to maintain the long periods of restrictive diet or vigorous exercise regimens necessary to achieve the durable results typically afforded by existing therapeutic options, but who demonstrate tolerant behavior during short periods when administered under supervision

Support for Mitochondrial Energy Production : Through its influence on lipid metabolism, AOD-9604 indirectly enhances mitochondrial ATP generation by increasing the availability of fatty acids as substrates for oxidation

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PSTPIP2 deficiency in mice causes osteopenia and increased differentiation of multipotent myeloid precursors into osteoclasts

Pathogenic alpha-synuclein aggregates preferentially bind to mitochondria and affect cellular respiration