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When evaluating by etiology of cirrhosis, median AFP values were 4.32 ng/mL in active HCV, 3.70 ng/mL in cured HCV, 3.33 ng/mL in ALD, 3.00 ng/mL in NAFLD, and 2.90 ng/mL in other cirrhosis (p 20 was 12.2% (n=949) in active HCV, 4.4% (n=906) in cured HCV, 2.4% (n=346) in ALD, 2.1% (n=188) in NAFLD, and 2.7% (n=150) in other cirrhosis (p 20 varies by almost 5-fold according to etiology of liver disease

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As a control, VpreB was added, and here, as expected from the cell-based experiments, no folding kinetics were detected (Fig