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21,22,23 As such, these alleles could produce truncated but (partially) active ADAMTS-2 enzymes lacking either the last TSP1 domain and the PLAC (protease and lacunin) domain (P1 and P2) or the two most C-terminal TSP1 domains and the PLAC domain (P5)

10.1038/s41398-019-0466-x Transl

This condition, manifested by episodes of acute pain in the proximal arm, presumably due to acute autoimmune inflammation of the nerves in the brachial plexus, is often associated with abnormal involuntary movements of the shoulder

Small intravenous human studies reported changes in sleep onset, sleep efficiency, total sleep time or daytime functioning in some settings

The FDA focuses on sellers and distributors, not personal users