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Derived from amino acids, creatine is a naturally occurring compound that plays a key role in the bodys ability to produce energy

This is corroborated by a retrospective study by Rennebaum et al., where PSC in 41 PSC-only patients showed accelerated disease progression compared to 115 IBD-PSC patients, and PSC-only patients had a higher risk of developing cirrhosis [204]

Although CoQ10 resulted in a significant increase in mean power during the WT5, the observed decreases in fatigue indexes following 100 mg CoQ10 administration did not differ from that seen with placebo administration [31]