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reported that leptin transport across the BBB varies with time of day, being significantly higher at night than during the day (46)

A real-world prospective cohort study including 2.2 million people demonstrated that the combination of SGLT-i and GLP-1 had better effects on all-cause mortality, MI and admission rate than SGLT-i or GLP-1 alone

This transient blockade can lead to a rebound increase in endogenous endorphins and enkephalins when the drug is cleared

RNA QuanTiseq analysis was performed on the contralateral brain hemispheres to those used for NMR (Group 3 in Fig S1C)

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