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Recently, Qiao and co-workers linked the biological functions and the redox homeostasis of melanocytes to the autophagy process, proving that suppression of ATG7-dependent autophagy inhibits proliferation and results in premature senescence of epidermal melanocytes

Gut microbiota promotes granulocyte-macrophage colony-stimulating factor (GM-CSF) production, which activates extracellular signal-regulated kinase signaling in alveolar macrophages to enhance airway defenses (Brown et al., 2017)

In an orthotopic glioma mouse model, combination therapy with DCA and radiotherapy significantly prolongs median survival, highlighting the potential utility of glucose metabolism inhibitors in overcoming resistance to TMZ/radiotherapy [82]

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2016;355:i5239